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Suggested citation for this article: Midgley CM, Baber JK, Biggs HM, et al. Use of trade names and commercial sources is for identification only and does not imply endorsement by the U. All HTML versions of MMWR articles are generated from final proofs through an automated process.Notes from the Field: Severe Human Metapneumovirus Infections — North Dakota, 2016. This conversion might result in character translation or format errors in the HTML version.HMPV is a cause of both upper and lower respiratory tract infections, including bronchiolitis and pneumonia, particularly among young children (1) and older adults (2).In the United States, the typical HMPV season extends from November–February through May–July (3).On May 27, 2016, CDC was informed by North Dakota Department of Health of a recent cluster of severe respiratory illnesses that included two deaths in children at a large hospital (hospital A) in Fargo, North Dakota, caused by human metapneumovirus (HMPV).

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Among the 27 adult patients (median age = 69 years), all were white, and all had underlying medical conditions, particularly chronic lung disease (19) or chronic heart disease (16).

Ten patients required either mechanical ventilation (two) or noninvasive ventilation (eight); among these 10 patients, nine reported chronic lung disease. Although 10 patients resided in long-term care facilities before hospital admission, no HMPV clusters were identified.

HMPV can cause severe respiratory illness in children and adults.

Users are referred to the electronic PDF version (https://gov/mmwr) and/or the original MMWR paper copy for printable versions of official text, figures, and tables.

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