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During the ten-day study period, the combined treatment group demonstrated significantly superior improvements in global ratings on day four, but not on day two or seven.

This study suggested some effectiveness of combined analgesic and muscle relaxant therapy when utilized early in the initial week of pain onset.

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Alfentanil or fentanyl are given by initial intravenous injection followed either by successive intravenous injections or an intravenous infusion.

Pain is often mistreated or undertreated and can lead to depression, insomnia, lethargy and reduced physical and mental functioning.

Successful control is more likely to be achieved if a proper assessment is made, which should include: The successful drug management of pain relies on selecting the appropriate drug at the correct dosage and balancing efficacy against adverse effects.

Professional Reference articles are written by UK doctors and are based on research evidence, UK and European Guidelines.

They are designed for health professionals to use, so you may find the language more technical than the condition leaflets.

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